基于中药质量常数的桂枝饮片等级评价

Grade evaluation of Cinnamomi Ramulus based on quality constant of traditional Chinese medicine

为了保证桂枝饮片的药效、促进市场高价值流通,依托质量常数法对桂枝饮片的质量等级进行评价研究。以从药材市场上收集的15批饮片为研究对象,测定其外在性状指标(饮片质量及厚度)和内在成分指标(桂皮醛含量);通过计算得到15批饮片的质量常数(A)和百分质量常数(A%),并根据结果对桂枝饮片进行等级划分。结果表明,15批桂枝饮片质量常数为0.85~28.11,百分质量常数为3.02%~100%,它们被划分为3个等级,即A≥22.49为一等饮片,14.01≤A<22.49为二等饮片,A<14.01为三等饮片;选取桂皮醛作为桂枝等级评价的内在成分指标合理可行;与传统等级评价方法相比,基于质量常数建立的等级评价方法可以将性状鉴别与成分含量相结合,综合、客观地对桂枝饮片进行等级划分,为中药材的生产、流通和监管提供参考。

In order to ensure the efficacy of Cinnamomi Ramulus decoction pieces and promote high-value circulation in the market,the quality grade evaluation of Cinnamomi Ramulus decoction pieces was researched based on the quality constant method.Taking 15 batches of decoction pieces collected from the medicinal material market as the research objects,the external characteristic indicators(quality and thickness of decoction pieces)and the intrinsic quality indicators(content of cinnamaldehyde)were measured.Then,the quality constant(A)and percentage quality constant(A%)were calculated and the grades of Cinnamomi Ramulus were classified according to the results.The results show that the quality constants of 15 batches of the decoction pieces were 0.85~28.11,and the percentage quality constants were 3.02%~100%.The 15 batches of Cinnamomi Ramulus were divided into three levels:GradeⅠ(A≥22.49),GradeⅡ(14.01≤A<22.49),GradeⅢ(A<14.01).It is reasonable and feasible to select cinnamaldehyde as the intrinsic quality indicators for the grade evaluation of Cinnamomi Ramulus decoction pieces.Compared with traditional grade evaluation methods,the grade evaluation method based on the quality constant can combine the identification of the traits with the content of the index components to classify Cinnamomi Ramulus decoction pieces comprehensively and objectively,which can provide a reference for the production,circulation and supervision of Chinese medicinal materials.