急诊科重点关注短缺药品替代药品目录的建立

Establishment of substitute list for the targeted shortage-drugs in the emergency department

目的研究急诊科重点关注短缺药品的替代药品,建立急诊科重点关注短缺药品替代药品目录。方法以国家卫生健康委员会指定的短缺药品为重点关注短缺药品,通过收集2个不同来源的药品使用与功能数据库,建立急诊科重点关注短缺药品备选替代药品初始目录;经过专家咨询与审定,并对33家三级甲等医疗机构进行问卷调查,确定重点关注短缺药品的替代药品及替代程度。结果在急诊科涉及的47种重点关注短缺药品中,有20种(42.6%)不能被替代,有17种(36.2%)可以被其他药品所替代,有10种(21.3%)可以考虑被其他药品替代。结论急诊科重点关注短缺药品不能被替代的比例高。对于不可替代的短缺药品、替代药和被替代药均为短缺的药品,应加强管理,提前预警,做好应对措施。

Objective To explore the alternative medicine of the shortage-drugs in the emergency department,and provide the evidence to establish the list of alternative drugs for the targeted shortage-drugs. Methods With the focus shortage drugs designated by the National Health Commission,the initial list of alternative drugs for shortage drugs in emergency department was established by collecting the drug use and function databases from two different sources. After expert consultation and approval,33 Grade-A medical institutions were investigated by questionnaire to determine the alternative drugs and the degree of substitution. Results Of total 47 shortage-drugs involved in the emergency department,20(42. 6%)could not be replaced,17(36. 2%)could be replaced by other drugs with the same formulation,and 10(21. 3%)could be considered to be replaced by other drugs with the same formulation. Conclusion The proportion of the shortage-drugs that can not be replaced in the emergency department is high. It is necessary to strengthen the management,early warning and response measures for the irreplaceable drugs in short supply and the drugs in short supply.