γ-和δ-酮酸衍生物均相催化氢化研究进展

Recent Progress in Homogeneous Catalytic Hydrogenation of γ- and δ-Ketoacid Derivatives

和δ-酮酸衍生物是最重要的双官能团生物质平台化合物之一,如何高效地催化这些酮酸类化合物转化成相应的单一精细化学品是当今研究的难点.我们综述了金属有机配合物均相催化氢化γ-和δ-酮酸的最新进展,重点介绍了用于催化生产γ-和δ-羟基酸、酯、内酯、环醚等的均相催化剂的结构、活性、选择性和反应机理.

γ-and δ-Ketoacid derivatives are one of the most important bifunctional biomass platform compounds. How to efficiently catalyze the hydrogenation of these ketoacid derivatives into the corresponding single fine chemicals is a difficult issue in the current research. This review focuses on recent progress related to homogeneously hydrogenated γ-/δ-keto acids catalyzed by metal-organic complexes as well as mainly introduces on the structure, activity, selectivity and reaction mechanism of homogeneous catalysts for the catalytic production of γ-and δ-hydroxy acids, esters, lactones, cyclic ethers, etc.