摘要
SAPHO综合征是一类以骨关节和皮肤病变为特点的罕见临床综合征,即出现滑膜炎(synovitis)、痤疮(acne)、脓疱病(pustulosis)、骨肥厚(hyperostosis)和骨炎(osteitis)等一系列病变。本文报道一例具有31年病史的非典型SAPHO综合征患者,经详细的诊断及鉴别诊断以及合理的诊疗方案的实施,最终患者病情获得明显改善。通过回顾并总结SAPHO综合征的临床诊疗特点,以及对该病例的讨论分析过程,充分体现了多学科诊疗在罕见病诊治中的有效性及必要性。
The SAPHO syndrome is a rare disease characterized by osteoarticular and dermatological manifestations.Here we reported an atypical case of SAPHO syndrome for 31 years.A multidisciplinary team made the diagnosis and differential diagnosis of the patient’s osteoarticular and dermatological lesions.Subse-quently,suitable treatment was initiated and the patient’s condition was significantly improved.At last,we reviewed and sum-marized the characteristics of diagnosis and treatment of SAPHO syndrome.The effectiveness and necessity of multidisciplinary treatment were demonstrated by the discussion and analysis of this rare disease.
作者
卢新宇
刘煜琛
李忱
叶雨芊
曹逸涵
刘炜
霍力
吴焕文
王涛
吴南
刘晓清
田欣伦
王木
朱惠娟
张文
张抒扬
LU Xinyu;LIU Yuchen;LI Chen;YE Yuqian;CAO Yihan;LIU Wei;HUO Li;WU Huanwen;WANG Tao;WU Nan;LIU Xiaoqing;TIAN Xinlun;WANG Mu;ZHU Huijuan;ZHANG Wen;ZHANG Shuyang(Clinical Medicine,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100005,China;Department of Traditional Chinese Medicine,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100730,China;Department of Radiology,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100730,China;Department of Nuclear Medicine,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100730,China;Department of Pathology,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100730,China;Department of Dermatology,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100730,China;Department of Orthopedics,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100730,China;Department of Infectious Diseases,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100730,China;Department of Pulmonary and Critical Care Medicine,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100730,China;Department of Stomatology,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100730,China;Department of Endocrinology,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100730,China;Department of Rheumatology and Immunology,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100730,China;Department of Cardiology,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100730,China)
出处
《协和医学杂志》
CSCD
2021年第3期417-422,共6页
Medical Journal of Peking Union Medical College Hospital
基金
国家重点研发计划罕见病临床队列研究(2016YFC0901500)
中国医学科学院医学与健康科技创新工程(2017-I2N-3-001)。
