霸王鞭的化学成分研究

Chemical constituents from Euphorbia royleana

对采自云南西双版纳的霸王鞭(Euphorbia royleana)地上部分进行了化学成分研究.采用正、反相硅胶柱层析,凝胶柱层析及半制备HPLC等分离技术,对霸王鞭的正丁醇提取物进行分离纯化,得到了7个单体化合物.过^(1)H NMR和^(13)C NMR波谱数据分析及文献对照,其结构鉴定为4′-甲氧基槲皮素(1)、taxifolin(2)、咖啡酸(3)、1,2,4-苯三酚(4)、尿囊素(5)、尿嘧啶(6)和肌醇(7).所有的化合物均首次从该植物中分离得到.

To study the chemical constituents of Euphorbia royleana collected from Xishuangbanna Prefecture of Yunnan province, the n-butanol extract of the aerial parts of this plant was fractionated by the normal and reversed-phase chromatography of silica gel, Sephadex LH-20, and semipreparative HPLC. Seven compounds were yielded and their structures were determined to be 4′-methoxyquercetin(1), taxifolin(2), feic acid(3), 1, 2, 4-benzenetriol(4), allantoin(5), uracil(6) and inositol(7) by means of 1 D NMR spectral analysis and a comparison with the reported literature. All of them were obtained from this species for the first time.