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美托洛尔对缺血性心力衰竭患者心功能及血清炎性因子水平的影响 被引量:1

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摘要 目的研究美托洛尔对缺血性心力衰竭患者心功能及血清C-反应蛋白(CRP)、白介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)水平的影响。方法选择荆州市第五人民医院2017年6月至2020年6月期间收治的180例缺血性心力衰竭患者,凭借随机数字表法,把所选取病例对象分成两个组,一个组为对照组(90例),另一个组为试验组(90例)。对照组患者接受曲美他嗪治疗,试验组患者在对照组基础上联合美托洛尔治疗,所有入选对象均连续治疗1个月。比对分析两组患者治疗后的临床疗效,治疗前后左心室射血分数(LVEF)、左心室舒张末期内径(LVEDD)、左心室收缩末期内径(LVESD)及血清CRP、IL-6、TNF-α水平。结果治疗后经计算发现,试验组与对照组患者临床总有效率分别为97.78%、82.22%,试验组高于对照组;两组患者血清TNF-α、CRP、IL-6及LVESD、LVEDD水平较治疗前均呈降低走向,且试验组降低幅度大于对照组;两组患者LVEF水平均呈升高走向,且试验组升高幅度大于对照组(均P<0.05)。结论美托洛尔联合曲美他嗪可增强缺血性心力衰竭患者的心功能,提高其临床疗效,且有效抑制机体炎性因子的表达,控制病情。
作者 宋建华 颜浩
出处 《现代医学与健康研究电子杂志》 2021年第9期59-61,共3页 Modern Medicine and Health Research
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