不宁腿综合征临床特点与规范化治疗

Clinical characteristics and standardized treatment of restless legs syndrome

不宁腿综合征(restless legs syndrome,RLS)是临床常见的运动感觉性神经系统疾病。主要表现为强烈、迫切想要移动肢体冲动/欲望,常常伴随着肢体深处不舒服或难以描述的感觉,夜间睡眠或安静时出现或加重,具有昼夜节律性,按摩或活动后缓解,安静时加重。本文将从RLS的发病机制、临床表现、诊断标准、鉴别诊断和治疗等方面进行系统综述。

Restless legs syndrome is a common motor-sensory disease of the nervous system.The main manifestations are an urge to move the legs,usually accompanied by or thought to be caused by uncomfortable and unpleasant sensations in the legs.These symptoms may begin or worsen during periods of rest or inactivity such as lying down or sitting and be partially or totally relieved by movement,such as walking or stretching,at least as long as the activity continues.This article will systematically review the pathogenesis,clinical manifestations,diagnostic criteria,differential diagnosis and treatment of restless legs syndrome.