细胞因子在创面修复中的研究进展

Research progress of cytokines in wound healing

多种细胞因子协同作用参与创面修复,虽然对细胞因子的研究很多,目前临床单纯使用细胞因子治疗创面并未起到理想的效果,今后细胞因子的序贯给药或者其给药系统研究可能是其促进慢性创面愈合的策略。本文就近年来主要的生长因子、趋化因子和炎症因子在创面修复中的研究进展进行综述。

A variety of cytokines work synergistically to participate in wound healing.Although there are many studies on cytokines,the current clinical use of cytokines to treat wounds has not achieved the desired effect.The sequential administration of cytokines or the study of its drug delivery system may be its strategy to promote chronic wound healing.This article reviews the research progress of major growth factors,chemokines and inflammatory factors in wound repair in recent years.