慢性自发性荨麻疹的严重程度及预后影响因素研究进展

Research progress of both disease severity and prognostic factors in chronic spontaneous urticaria

慢性自发性荨麻疹是临床上常见的疾病,与肥大细胞激活有关,慢性自发性荨麻疹的不可预测性及病程迁延给患者带来了很大的困扰,并严重影响患者的身心健康。一些临床相关因素(如年龄、病程、早期使用激素治疗、是否合并可诱导荨麻疹、自身免疫性疾病)以及实验室生物学相关因素(如凝血功能异常,血清中维生素D、白介素-24等的水平)对于慢性自发性荨麻疹的病情评估、治疗管理及预后判断具有十分重要的意义。本文综述慢性自发性荨麻疹的严重程度及预后影响因素。

Chronic spontaneous urticaria(CSU)is a common clinical disease,which is related to mast cell activation.Due to the unpredictability and chronic course,CSU brings great concerns to patients,and seriously affects patients’physical and mental health.Some clinical and laboratory biological markers play very important roles in the evaluation,treatment management and prognosis of CSU.This article reviews the severity and prognostic factors of chronic spontaneous urticaria.