基于单中心的乳腺癌合并心房颤动患病率调查

A single-center study on the prevalence of atrial fibrillation in breast cancer patients

目的:探讨乳腺癌患者的心房颤动(房颤)发生情况。方法:选择2020年7月至2020年12月上海交通大学医学院附属第九人民医院黄浦分院乳腺外科收治的经手术及病理确诊的乳腺癌患者706例,收集患者年龄、房颤病史、高血压病史、糖尿病病史、心衰病史、脑卒中病史等,对房颤患者进行CHADS2评分。结果:706例乳腺癌患者中,合并房颤21例,患病率为2.97%,高于整体人群的1.70%(P<0.05)。乳腺癌合并房颤患者的平均CHADS2评分为(2.19±1.33)分,合并高血压(76.19%vs 28.76%)、心衰(14.29%vs 0)、脑卒中(42.86%vs 1.61%)的比例高于无房颤患者(P<0.05)。结论:乳腺癌合并房颤较为常见,合并房颤患者并发其他心脑血管病比例也升高,临床工作中应予以重视。

Objective:To explore the incidence of atrial fibrillation in patients with breast cancer.Methods:A total of 706 breast cancer patients diagnosed by surgery and pathology admitted to the Department of Breast Surgery,Huangpu Branch of Shanghai Ninth People’s Hospital,Shanghai Jiao Tong University School of Medicine from July 2020 to December 2020 were included.Age,histories of atrial fibrillation,hypertension,diabetes,heart failure,and stroke were analyzed according to the medical history data.For patients with atrial fibrillation,the CHADS2 score was performed.Results:The rate of atrial fibrillation(2.97%)in breast cancer patients was significantly higher than that in the total population(1.70%,P<0.05).The CHADS2 score of breast cancer patients with atrial fibrillation was 2.19±1.33,and the proportions of patients with hypertension(76.19%vs 28.76%),heart failure(14.29%vs 0),and stroke(42.86%vs 1.61%)were higher than those of patients without atrial fibrillation(P<0.05).Conclusions:Atrial fibrillation is more common in breast cancer patients,among them,the proportions of patient with other cardiovascular or cerebrovascular diseases increases.which needs more attention.