摘要
基质金属蛋白酶-2(MMP-2)是基质金属蛋白酶(MMPs)家族中的一员,它的异常表达近年来被证明与多种疾病的发生发展有关,其在眼科疾病中起着重要作用。现笔者对MMP-2在眼组织中的表达、检测以及在眼病中的作用进行总结。
Matrix metalloproteinase-2(MMP-2)is one of the matrix metalloproteinase proteins.Its abnormal expression has been proven to be related to the occurrence and development of various ophthalmic diseases in recent years.We summarize the expression and detection of MMP-2 in the eye and the effects of MMP-2 in ophthalmic diseases.
作者
蒋润
周激波
Run Jiang;Jibo Zhou(Department of Ophthalmology,Ninth People's Hospital,Shanghai JiaoTong University School of Medicine,Shanghai 200011,China;Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology,Shanghai 200011,China)
出处
《中华眼视光学与视觉科学杂志》
CAS
CSCD
2021年第4期312-316,共5页
Chinese Journal Of Optometry Ophthalmology And Visual Science
基金
上海市科学技术委员会项目(17DZ2260100)。
关键词
基质金属蛋白酶
基质金属蛋白酶-2
近视
青光眼
黄斑变性
白内障
matrix metalloproteinase proteins
matrix
metalloproteinase-2
myopia
glaucoma
macular degeneration
cataract