面向临床科研的全院级医疗大数据平台建设与数据治理实践探索

Development of a big medical database system for clinical research and practice of medical data governance

目的加强医疗数据资源整合共享,为临床科研人员提供高质量、可利用的数据,推进医疗数据在临床科研中的深入应用.方法根据全院级医疗大数据平台的建设和应用目标,将多个主要临床业务信息系统的数据整合后进行数据清洗、加工和解析,最终汇聚到统一平台中,形成有价值、可被利用的数据资源.结果构建面向临床科研的全院级医疗大数据平台,该平台累积了北京大学人民医院自2004年以来,1342万余名患者的5000万余次就诊数据,设计了面向分析的医院科研通用数据模型,并能够按照模型在平台上进行科研数据查询与导出,建立了医院临床科研数据管理规范和服务机制.结论医疗大数据平台的建设及数据治理实践为北京大学人民医院基于医疗大数据的高水平科技攻关提供了高质量数据基础,进一步提升了临床科研效率和质量.同时,在确保数据安全、合规利用的基础上,从全院视角对临床科研数据进行了管控.

Objective To strengthen the integration and sharing of medical data resources,provide high-quality and usable data for clinical researchers,and promote the medical data use in clinical research.Methods According to the development and application goals of the medical big data platform,data from different major clinical information systems in our hospital are integrated and then cleaned,processed and analyzed,and finally aggregated into a unified platform and turned to valuable and usable data resources.Results A medical big data platform for clinical research in our hospital has been developed.It has stored over 13.42 million patients'clinical data of more than 50 million visits since 2004 in our hospital;an analysis-oriented common data model(CDM)for clinical research has been designed;clinical researchers can query and extract clinical data according to CDM;the standard clinical research data service mechanisms have been established.Conclusions The medical big data platform in our hospital helps to provide usable data of good quality for high-level scientific research based on medical big data»and improve the efficiency and quality of clinical research;at the same times it also provides a efficient way to manage and control clinical research data use while ensuring data security and regulatory compliance.