穴位敷贴联合针灸对晚期食管癌患者吞咽功能、癌因性疲乏的影响

Effects of acupoint application combined with acupuncture and moxibustion on swallowing function and cancer-related fatigue in patients with advanced esophageal cancer

目的:探究应用穴位敷贴联合针灸对晚期食管癌患者吞咽功能以及癌因性疲乏的影响。方法:采用便利抽样法,选取河北北方学院附属第一医院2016年9月—2019年9月收治的100例晚期食管癌患者作为研究对象,按照住院号奇偶数随机分组原则将患者分为常规组及联合组,每组各50例。常规组采用常规方式干预,联合组在常规组基础上加用针灸与穴位敷贴干预。比较两组患者的吞咽功能、癌因性疲乏、生活质量、中医证候积分及干预效果。结果:干预后联合组吞咽功能优良率高于常规组,差异有统计学意义(P<0.05)。两组患者干预后Piper疲乏修订量表得分低于干预前,且联合组干预后得分低于常规组,差异有统计学意义(P<0.05)。联合组患者干预后生活质量评定量表得分高于常规组,中医证候积分低于常规组,差异均有统计学意义(P<0.05)。联合组患者干预总有效率为90.0%(45/50),高于常规组的70.0%(35/50),差异有统计学意义(P<0.05)。结论:晚期食管癌患者采用穴位敷贴联合针灸进行干预可以有效改善吞咽功能以及相关中医证候,缓解癌因性疲乏,减轻化疗对患者生活质量的影响。

Objective To explore effects of acupoint application combined with acupuncture and moxibustion on swallowing function and cancer-related fatigue in patients with advanced esophageal cancer.Methods Using the convenient sampling method,a total of 100 patients with advanced esophageal cancer admitted to the First Affiliated Hospital of Hebei North University from September 2016 to September 2019 were selected as the research objects.According to the principle of odd and even of inpatient number,the patients were divided into the conventional group and the combined group,with 50 cases in each group.The conventional group used conventional methods for intervention,while the combined group used acupuncture and moxibustion and acupoint application intervention on the basis of the conventional group.The swallowing function,cancer-related fatigue,quality of life,traditional Chinese medicine(TCM)syndrome points and the intervention effect were compared between the two groups.Results After the intervention,the excellent and good rate of swallowing function of patients of the combined group was higher than that of the conventional group,and the difference was statistically significant(P<0.05).After the intervention,the score of the Revised Piper Fatigue Scale(PFS-R)in two groups were lower than those before the intervention,and the score of PFS-R of the combined group was lower than that of the conventional group after the intervention,and the differences were statistically significant(P<0.05).After the intervention,the score of the Quality of Life Rating Scale in the combined group was higher than that in the conventional group,and the score of the TCM syndrome in the combined group was lower than that in the conventional group with statistical significance(P<0.05).The total effective rate of intervention for patients in the combined group was 90.0%(45/50),which was higher than 70.0%(35/50)of the conventional group,and the difference was statistically significant(P<0.05).Conclusions The intervention of acupoint application combined with acupuncture and moxibustion in patients with advanced esophageal cancer can effectively improve swallowing function and related TCM syndromes,relieve cancer-related fatigue and reduce the effect of chemotherapy on the quality of life of patients.