急性缺血性脑卒中患者血压变异性与预后相关性的研究进展

Correlation Between Blood Pressure Variability and Prognosis in Patients with Acute Ischemic Stroke

高血压是缺血性脑卒中的主要危险因素,而血压变异性(BPV)是独立于平均血压水平的影响缺血性脑卒中发生的又一危险因素。近年来,针对BPV的研究逐渐成为脑卒中防治领域的热点,但缺血性脑卒中急性期BPV与预后的关联尚不完全清楚。现就BPV的概念及分类、病理生理机制、BPV与脑血流自动调节的关系、BPV与缺血性脑卒中的临床研究及影响机制进行综述。

Hypertension is the main risk factor of ischemic stroke,and blood pressure variability(BPV)is another risk factor independent of the average blood pressure level.In recent years,the research on BPV has gradually become a hot spot in the field of stroke prevention and treatment,but the relationship between BPV and prognosis in acute ischemic stroke is not completely clear.This article reviews the concept and classification of BPV,pathophysiological mechanism,the relationship between BPV and cerebral blood flow autoregulation,and the clinical research and influence mechanism of BPV and ischemic stroke.