摘要
A pandemic is a disease that spreads worldwide.When disease is new such as coronavirus disease 2019(COVID-19),evidentiary basis,by definition,to prevent,diagnose,and treat the disease is limited.Nevertheless,clinical practice guidelines are urgently required to assist policy and healthcare workers to make informed decisions.But,acting in the high-quality evidentiary vacuum,that is,basing guidelines on poor-quality research can be counterproductive and potentially harmful.[1,2] Thus,guideline developers face a number of challenges during a pandemic like COVID-19 that we wish to address in this paper.
