病原菌耐药监测分析指标评价体系构建的探索

Exploration on the construction of analysis indicators system for antibiotic resistancemonitoring

当前我国病原菌耐药性问题严重,我国在多领域已分别建立的耐药监测网络,由于监测技术方法不统一,信息碎片化,无法显示我国病原菌耐药的整体流行趋势和传播规律。因此需构建全国多领域的病原菌耐药监测网络平台,揭示我国病原菌耐药发生、发展和传播规律。监测平台中需要使用相匹配的分析指标评价体系。本研究拟探索出一套科学合理的耐药监测分析指标,适用于包括人群、畜牧养殖、环境和食品相关环节等在内的耐药性数据监测与分析。经对我国5个耐药监测网络的调查分析,结合文献及专家调研,初步构建了包含15个病原菌耐药监测分析指标的评价体系,为我国的病原菌耐药监测网络数据收集、整理、评价及预测、预警体系的构建提供基础。

Antibiotic resistance(AR)is a severe and fast-growing public health challenge with rapid globalization,especially in China.Although some monitoring systems were established in different fields,fragmentation of information failed to show the overall trend and spread of AR.It is necessary to establish a national monitoring system to reveal the occurrence,development,and spread of AR.The new AR monitoring system needs an updated analysis indicators system.We intend to recommend a new analysis indicators system for AR was constructed and applied to AR data monitoring and analysis for humans,animals,the environment,and foods.After investigating and analyzing the 5 Chinese major AR monitoring systems and literature,we have formulated 15 AR monitoring analysis indicators and initially established an evaluation system for the country's new AR monitoring system.