聚乙二醇4000联合麻仁软胶囊治疗儿童便秘的临床疗效分析

Clinical efficacy of polyethylene glycol 4000 combined with Maren soft capsule in children with constipation

目的探讨聚乙二醇4000联合麻仁软胶囊在儿童便秘上的临床疗效。方法120例便秘患儿,随机分为对照组和研究组,每组60例。对照组应用基础治疗联合聚乙二醇4000用药治疗,研究组在对照组基础上联合麻仁软胶囊治疗。比较两组患儿伴随症状消失时间、临床疗效。结果研究组腹胀、便秘、厌食、腹痛症状消失时间分别为(2.3±1.2)、(1.5±1.4)、(1.8±0.7)、(1.1±0.9)d,均短于对照组的(4.2±2.4)、(4.6±2.3)、(3.7±1.8)、(3.1±1.5)d,差异均具有统计学意义(P<0.05)。研究组治疗总有效率96.7%高于对照组的86.7%,差异具有统计学意义(P<0.05)。结论儿童便秘的治疗中,在基础治疗之上合并聚乙二醇4000及麻仁软胶囊治疗的效果理想,伴随症状持续时间短,临床上应当进一步推广应用。

Objective To discuss the clinical efficacy of polyethylene glycol 4000 combined with Maren soft capsule in children with constipation.Methods A total of 120 children with constipation were randomly divided into control group and research group,with 60 cases in each group.The control group received basic therapy and polyethylene glycol 4000,and the research group received polyethylene glycol 4000 combined with Maren soft capsule.The disappearance time of accompanying symptoms and clinical efficacy of the two groups were compared.Results The disappearance time of abdominal distension,constipation,anorexia,abdominal pain of the research group was(2.3±1.2),(1.5±1.4),(1.8±0.7)and(1.1±0.9)d,which was shorter than(4.2±2.4),(4.6±2.3),(3.7±1.8)and(3.1±1.5)d of the control group,and the difference was statistically significant(P<0.05).The total effective rate 96.7%of the research group was higher than 86.7%of the control group,and the difference was statistically significant(P<0.05).Conclusion In the treatment of constipation in children,the effect of polyethylene glycol 4000 and Maren soft capsule on the basis of basic treatment is ideal,and the duration of adverse reactions is short,which should be further promoted and applied in clinic.