老年CHD患者使用他汀类药物的现状、特点及影响因素

Status,characteristics and influencing factors of statins in elderly patients with CHD

目的分析老年冠心病(CHD)患者使用他汀类药物的现状、特点,并分析其使用的影响因素。方法选取2301例老年CHD患者作为研究对象,收集分析患者的临床资料,统计他汀类药物使用情况、特点及使用的影响因素。结果2301例老年CHD患者中,1325例(57.58%)患者使用他汀类药物;其中阿托伐他汀使用率最高,占比为22.16%;其次为瑞舒伐他汀,占比为20.17%;使用率最低的是洛伐他汀,占比为1.22%。文化程度、月收入、病程、合并缺血性脑卒中、经皮冠状动脉(冠脉)腔内成形术及冠脉旁路移植术是影响使用他汀类药物的单因素(P<0.05)。Logistic分析显示,文化程度、月收入、病程、合并缺血性脑卒中、经皮冠脉腔内成形术及冠脉旁路移植术是使用他汀类药物的影响因素(P<0.05)。结论老年CHD患者中他汀类药物使用率偏低,多数使用阿托伐他汀;文化程度、月收入、病程、合并缺血性脑卒中、经皮冠脉腔内成形术及冠脉旁路移植术是使用他汀类药物的影响因素。

Objective To analyze the status and characteristics and influencing factors of statins in elderly patients with chronic heart disease(CHD).Methods There were 2301 elderly CHD patients as study subjects.The clinical data of patients was collected and analyzed,and the use,characteristics and influencing factors of statins were statistically analyzed.Results Among 2301 elderly CHD patients,1325 cases(57.58%)used statins;among them,atorvastatin had the highest usage rate,accounting for 22.16%;followed by rosuvastatin,accounting for 20.17%;the lowest usage rate was lovast statins,accounting for 1.22%.Education level,monthly income,course of disease,combined ischemic stroke,percutaneous coronary transluminal angioplasty and coronary artery bypass grafting were the influencing factors that affect the use of statins(P<0.05).Logistic analysis showed that education level,monthly income,course of disease,combined ischemic stroke,percutaneous transluminal coronary angioplasty and coronary artery bypass grafting were the influencing factors for the use of statins(P<0.05).Conclusion The usage rate of statins in elderly CHD patients is low,and most of them use atorvastatin.Education level,monthly income,course of disease,combined ischemic stroke,percutaneous coronary transluminal angioplasty and coronary artery bypass grafting are the influencing factors that affect the use of statins.