致病性尖孢镰刀菌毒力因子的研究进展

Virulence Factors of Pathogenic Fusarium oxysporum: Research Progress

致病性尖孢镰刀菌(Fusarium oxysporum)侵染植物引发的植物枯萎病是世界范围内广泛存在的毁灭性土传真菌病害,目前该菌已被列为世界上第五大植物病原真菌。由于病原菌通过土壤传播,其致病机理尚未完全明确,而充分了解尖孢镰刀菌的致病机制是对抗这种疾病的先决条件。为了更好的研究和实施有效控制策略从而限制宿主植物感染,本文归纳了尖孢镰刀菌的致病机理,总结了毒力因子中的细胞壁降解酶、毒素、信号传导途径(MAPK通路)对致病进程的影响,分析了毒力基因及转录因子在感染过程中的调控机理。以期能为防控尖孢镰刀菌引起的枯萎病提供作用靶点和理论依据。

Plant wilt disease triggered by pathogenic Fusarium oxysporum infecting plant is a devastating soil borne fungal disease that is widespread in the world, and the fungi are currently ranked as the fifth most phytopathogenic fungi in the world. Because the pathogen is transmitted through the soil, its pathogenic mechanism has not been fully defined, and a full understanding of the pathogenic mechanism of F. oxysporum is a prerequisite for combating this disease. To better explore and implement the effective control strategies and thus limit host plant infection, this review concludes the pathogenesis of F. oxysporum, summarizes the contribution of cell wall degrading enzymes, toxins, signaling pathways(MAPK pathways) in virulence factors to the pathogenic process, and analyzes the regulatory mechanisms of virulence genes and transcription factors during infection. It is hoped to provide targets and rationale for controlling wilt diseases caused by F.oxysporum.