儿童青少年抑郁症自杀及相关影响因素研究

Study on the characteristics of the suicide and the related factors in children and adolescents with depressive disorder

目的探讨儿童青少年抑郁症患者中自杀相关影响因素。方法选取2018年1月至2019年12月就诊于河北省第六人民医院的389例儿童青少年抑郁症患者作为研究对象,其中自杀组171例,非自杀组218例。对两组间的一般情况与临床特征进行比较,并采用Logistic回归方法对青少年儿童抑郁症伴自杀的影响因素进行分析。结果自杀组和非自杀组在年龄(t=-2.23,P=0.026)、躯体疾病(χ^(2)=5.65,P=0.017)、精神病性症状(χ^(2)=4.28,P=0.038)、睡眠障碍(χ^(2)=5.69,P=0.017)、治疗情况(药物治疗:χ^(2)=40.31,P<0.001;心理治疗:χ^(2)=5.81,P=0.016)方面差异有统计学意义。Logistic回归分析显示,年龄(OR=0.59,95%CI:0.45~0.78)、精神病性症状(OR=2.20,95%CI:1.02~4.76)、躯体疾病(OR=0.08,95%CI:0.04~0.18)与自杀相关。结论年龄、精神病性症状、躯体疾病是儿童青少年抑郁自杀的相关影响因素。

Objective To explore the characteristics of the suicide and the related factors in children and adolescents with depressive disorder.Methods From January 2018 to December 2019,a total of 389 children and adolescents admitted to Hebei Provincial Sixth People's Hospital with depressive disorder were recruited,with 171 patients in suicide group,and 218 patients in non-suicide group.The general and clinical information were compared between the two groups.Logistic regression was used to analyze the related factors of the suicide in children and adolescents with depressive disorder.Results There were significant differences between the two groups in age(t=-2.23,P=0.026),physical diseases(χ^(2)=5.65,P=0.017),psychotic symptoms(χ^(2)=4.28,P=0.038),sleep disorder(χ^(2)=5.69,P=0.017)and the treatments(drug treatments:χ^(2)=40.31,P<0.001;pyschological treatments:χ^(2)=5.81,P=0.016).Logistic regression analysis showed that age(OR=0.59,95%CI:0.45-0.78),psychotic symptoms(OR=2.20,95%CI:1.02-4.76)and physical diseases(OR=0.08,95%CI:0.04-0.18)were related to suicide.Conclusions Age,psychotic symptoms and physical diseases are the related factors to the suicide in children and adolescents with depressive disorder.