乳腺癌患者彩色多普勒超声征象与雌孕激素受体和CerbB-2的相关性

Correlations between color Doppler ultrasound signs of breast cancer patients and estrogen receptor,progesterone receptor,CerbB-2

目的分析乳腺癌患者彩色多普勒超声征象与雌激素受体(ER)、孕激素受体(PR)和CerbB-2的相关性。方法随机选取2018年1月-2019年7月就诊的78例乳腺癌患者,均接受彩色多普勒超声检查,测定ER、PR、CerbB-2阳性率。结果 78例乳腺癌患者中,43例ER阳性,40例PR阳性,39例CerbB-2阳性。ER阳性患者的肿块边缘毛刺征、肿块血流为乏血供型比例显著高于ER阴性患者(均P<0.05)。PR阳性患者的肿块边缘无毛刺征、肿块血流为乏血供型比例显著高于PR阴性患者(均P<0.05)。CerbB-2阳性患者的肿块血流为富血供型比例显著高于CerbB-2阴性患者(均P<0.05)。结论乳腺癌患者彩色多普勒超声征象与ER、PR、CerbB-2有相关性,联合检测有助于判断乳腺癌恶性程度及预后。

Objective To analyze the correlations between color Doppler ultrasound signs of breast cancer patients and estrogen receptor( ER),progesterone receptor( PR),CerbB-2. Methods Seventy-eight breast cancer patients were selected from January 2018 to July 2019 randomly,color Doppler ultrasonography was performed,the positive rates of ER,PR,and CerbB-2 were detected. Results Among 78 breast cancer patients,the numbers of patients with positive ER,PR,and CerbB-2 were 43,40,and 39,respectively. The proportions of patients with spicule sign of mass margin and hypovascular mass in ER positive patients were statistically significantly higher than those in ER negative patients( P<0. 05). The proportions of patients with spicule sign of mass margin and hypovascular mass in PR positive patients were statistically significantly higher than those in PR negative patients( P<0. 05). The proportion of patients with hypervascular mass in CerbB-2 positive patients was statistically significantly higher than that in CerbB-2 negative patients( P<0. 05). Conclusion Color Doppler ultrasound signs of breast cancer patients are correlated with ER,PR,and CerbB-2,joint detection is helpful to judging malignant degree and prognosis of breast cancer.