右美托咪定、地佐辛对全麻老年患者全膝关节置换术后早期睡眠的影响

Effects of Dexmedetomidine and Dezocine on Early Sleep after Total Knee Arthroplasty in Elderly Patients under General Anesthesia

目的:探讨右美托咪定地佐辛对全麻老年患者全膝关节置换术后早期睡眠的影响。方法:选取2018年1月至2019年6月在中山大学附属第三医院粤东医院,接受全膝关节置换术治疗的患者98例作为研究对象,采用随机数表法分为观察组和对照组,每组49例。观察组静脉泵注右美托咪定、地佐辛,对照组输注相同剂量的氯化钠注射液,比较2组麻醉效果。结果:观察组术后早期睡眠显著优于对照组(P<0.05)。结论:老年患者全膝关节置换术采用右美托咪定复合地佐辛,能够明显提高患者早期睡眠质量。

Objective:To investigate the effect of dexmedetomidine on early sleep after total knee arthroplasty in elderly patients under general anesthesia.Methods:January 2018-June 2019 in our hospital underwent total knee replacement treatment of 98 patients,divided into two groups by random indicator method(49 cases),including 49 cases in anesthesia induced by intravenous infusion right before the microphones set,push intravenous injection before the cut leather with sheen,as observation group,49 cases of the same dose of sodium chloride injection,infusion as control group,compared two groups of narcotic effect.Results:The observation group was significantly better than the control group in early postoperative sleep(P<0.05).Conclusion:Dexmedetomidine combined with dezocine can significantly improve the quality of early sleep in elderly patients undergoing total knee arthroplasty.