改良小切口手术治疗甲状腺微小癌的效果及对甲状腺功能的影响

Modified small incision surgery for the treatment of thyroid microcarcinoma and its influence on thyroid function

目的探讨改良小切口手术治疗甲状腺微小癌的效果及对甲状腺功能的影响。方法选取2017年2月至2019年6月本院外科收治的84例择期行手术治疗的微小甲状腺癌患者作为研究对象,随机分为对照组和观察组,每组42例。对照组行传统甲状腺切除术,观察组行改良小切口甲状腺切除术。比较两组手术相关指标、甲状腺激素水平、应激指标及术后并发症发生率。结果观察组切开长度、手术时间、住院时间均短于对照组,术中出血量少于对照组(P<0.05);观察组TSH、T4及T3水平均低于对照组(P<0.05);观察组hsCRP、COR及E水平均低于对照组(P<0.05);观察组术后并发症发生率为9.52%,明显低于对照组的26.19%(P<0.05)。结论改良小切口手术治疗甲状腺微小癌患者疗效显著,可有效缩短手术时间,减少术中出血量,改善机体甲状腺功能,降低应激反应及术后并发症发生率,值得临床推广应用。

Objective To explore the effect of modified small incision surgery in the treatment of thyroid microcarcinoma and its influence on thyroid function.Methods 84 patients with elective surgical treatment of thyroid microcarcinoma who were admitted to the hospital from February 2017 to June 2019 were selected as the research subjects.They were randomly divided into control group and observation group,with 42 cases in each group.The control group underwent traditional thyroidectomy,and the observation group underwent modified small incision surgery.The operation-related indicators,thyroid hormone levels,stress indicators and postoperative complications were compared between two groups.Results The length of incision,operation time and hospital stay in the observation group were shorter than those in the control group,and intraoperative blood loss was less than that in the control group(P<0.05);the TSH,T4 and T3 levels in the observation group were lower than those in the control group(P<0.05);the hsCRP,COR and E levels of the observation group were lower than those of the control group(P<0.05);the postoperative complication rate of the observation group was 9.52%,which was significantly lower than 26.19% of the control group(P<0.05).Conclusion Modified small incision surgery is effective in treating patients with thyroid microcarcinoma.It can effectively shorten the operation time,reduce intraoperative blood loss,improve the body's thyroid function,reduce stress response and postoperative complications,and is worthy of clinical application.