经尿道钬激光膀胱肿瘤切除术与经尿道膀胱肿瘤电切术治疗浅表层膀胱癌的疗效和安全性比较

Comparison of the efficacy and safety of transurethral holmium laser bladder tumor resection and transurethral resection of bladder tumors in the treatment of superficial bladder cancer

目的探究经尿道钬激光膀胱肿瘤切除术(HOLRBT)与经尿道膀胱肿瘤电切术(TURBT)治疗浅表层膀胱癌的疗效和安全性。方法选取2017年12月至2019年12月于本院治疗的60例浅表层膀胱癌患者作为研究对象,随机分为观察组与对照组,每组30例。对照组行TURBT术式治疗,观察组行HOLRBT术式治疗,比较两组手术相关指标、住院时间、炎症因子水平及并发症发生率。结果观察组出血量明显低于对照组,膀胱冲洗、尿管留置、住院等时间均明显短于对照组(P<0.05);观察组IL-6、IL-8、TNF-α水平均明显低于对照组(P<0.05);观察组并发症发生率为3.33%,明显低于对照组的20%,差异有统计学意义(P<0.05)。结论浅表层膀胱癌患者采取HOLRBT术式治疗可降低出血量,缩短术后恢复时间,减少并发症发生,与TURBT术式比较具有一定优势。

Objective To explore the efficacy and safety of transurethral holmium laser bladder tumor resection(HOLRBT)and transurethral resection of bladder tumor(TURBT)in the treatment of superficial bladder cancer.Methods 60 patients with superficial bladder cancer who were treated in the hospital from December 2017 to December 2019 were selected as the research subjects,and they were randomly divided into observation group and control group,with 30 cases in each group.The control group was treated with TURBT operation,and the observation group was treated with HOLRBT operation.The operation-related indicators,hospital stay and the incidence of complications were compared between the two groups.Results The bleeding volume of the observation group was significantly lower than that of the control group,and the time of bladder irrigation,catheter indwelling and hospitalization was significantly shorter than that of the control group(P<0.05).The levels of IL-6,IL-8 and TNF-αin the observation group were significantly lower than those in the control group(P<0.05);the complication rate of the observation group was 3.33%,which was significantly lower than 20%of the control group,the difference is statistically significant(P<0.05).Conclusion HOLRBT surgery for patients with superficial bladder cancer can reduce blood loss,shorten postoperative recovery time,and reduce complications.Compared with TURBT surgery,it has certain advantages.