探讨宫腹腔镜治疗对女性不孕症患者临床疗效及对生殖激素的影响

To investigate the clinical eff ect of laparoscopic treatment on female infertility and the eff ect on reproductive hormone

目的分析宫腹腔镜治疗女性不孕症患者的临床疗效及对生殖激素的影响。方法选取100例女性不孕症患者,采用随机数字表法分为研究组与对照组,各50例。对照组患者采用宫腔镜治疗,研究组患者采用宫腹腔镜治疗。比较两组患者临床疗效、治疗前后生殖激素浓度水平及宫内妊娠情况。结果研究组治疗总有效率为94.00%,显著高于对照组的76.00%,差异有统计学意义(P<0.05)。治疗前,两组患者促黄体生成素(LH)、促卵泡生成激素(FSH)、雌二醇(E2)水平比较,差异无统计学意义(P>0.05);治疗后,两组患者LH、FSH水平均明显低于治疗前,E2水平明显高于治疗前,且研究组明显优于对照组,差异具有统计学意义(P<0.05)。研究组患者宫内妊娠率为60.00%,显著高于对照组的30.00%,差异具有统计学意义(P<0.05)。结论在女性不孕症患者的治疗过程中,宫腹腔镜治疗方案明显优于宫腔镜,能够有效促进患者体内激素水平的改善,同时显著提升宫内妊娠率,值得临床推广与应用。

Objective To analyze the clinical effect of laparoscopic treatment of female infertility and its effect on reproductive hormones.Methods A total of 100 female infertile patients were selected and divided into study group and control group by random number table method,with 50 cases in each group.Patients in the control group were treated with hysteroscopy,and patients in the study group were treated with laparoscopy.Clinical effi cacy,reproductive hormone concentration and intrauterine pregnancy before and after treatment were compared between 2 groups.Results The total eff ective rate of the study group was 94.00%,which was signifi cantly higher than that of the control group(76.00%),the diff erence was statistically signifi cant(P<0.05).Before treatment,there were no signifi cant diff erences in the levels of luteinizing hormone(LH),follicle-stimulating hormone(FSH)and estradiol(E2)between 2 groups(P>0.05).After treatment,the levels of LH and FSH in 2 groups were significantly lower than before treatment,the levels of E2 were signifi cantly higher than before treatment,and the study group was signifi cantly better than the control group,the diff erence was statistically signifi cant(P<0.05).The rate of intrauterine pregnancy in the study group was 60.00%,signifi cantly higher than that in the control group(30.00%),and the diff erence was statistically signifi cant(P<0.05).Conclusion In the treatment process of female infertility patients,uterine laparoscopy is signifi cantly better than hysteroscopy,which can eff ectively promote the improvement of hormone levels in patients and signifi cantly improve the intrauterine pregnancy rate,which is worthy of clinical promotion and application.