上海某社区提升骨质疏松症患者用药依从性的干预研究

Intervention study on improving medication compliance of patients with osteoporosis in a community in Shanghai

【目的】评价社区骨质疏松症患者接受健康教育后其用药依从性及骨密度的改善效果。【方法】选择123名骨质疏松症患者为研究对象,A社区64名患者为对照组,B社区59名患者为干预组,分别给予不同的健康教育指导,2年后比较两组骨质疏松知识掌握情况、健康行为、用药依从性和骨密度变化情况。【结果】干预组在干预前后对除“锻炼身体到什么程度比较好”以外的骨质疏松问题的正确率明显提高(P <0.05);干预组在干预前后的健康行为和用药依从性明显改善(P <0.05);干预组对骨质疏松知识的掌握情况、多数的健康行为、用药依从性均优于对照组(P <0.05);干预组和对照组骨密度T值在干预前后的差值分别为0.025±0.322和-0.139±0.312,两组差异有统计学意义(P <0.05)。【结论】对骨质疏松症患者开展健康教育,能够提高患者健康行为和治疗依从性,改善骨密度状况,控制骨质疏松症病情。

[Objective]To determine the effects of health education on medication compliance and bone mineral density of patients with osteoporosis in community.[Methods]A total of 123 patients with osteoporosis in A and B community(64 patients in control group and 59 patients in intervention group)received diverse health education and guidance.After a 2-year intervention,knowledge of osteoporosis,health behavior,medication compliance and bone mineral density change were compared between the two groups.[Results]In the intervention group,the proportions of correctly responding to the questions of osteoporosis were significantly improved before and after intervention(P<0.05),except the questions of“exercise to what extent is better”.Similarly,health behavior and medication compliance were also significantly improved in the intervention group(P<0.05).In addition,knowledge of osteoporosis,most health behavior and medication compliance were better than those in the control group(P<0.05).The difference in the bone mineral density between the intervention group and the control group before and after intervention was 0.025±0.322 and-0.139±0.312(P<0.05),respectively,showing significant differences(P<0.05).[Conclusion]Health education for patients with osteoporosis may significantly improve health behavior,medication compliance,bone mineral density,and prognosis of osteoporosis.