麒麟丸联合克罗米芬治疗肾虚型排卵障碍性不孕的临床研究

Clinical Study of Qilin Pills Combined with Clomiphene in the Treatment of Infertility Patients with Kidney Deficiency due to Ovulation Dysfunction

目的分析研究麒麟丸联合克罗米芬治疗肾虚型排卵障碍性不孕的临床疗效。方法选取中医辨证属于肾虚型排卵障碍性不孕的患者共68例,按照随机数据表分为观察组34例和对照组34例,对照组予以克罗米芬治疗,治疗组在克罗米芬的基础上加用中成药麒麟丸治疗,观察2组患者的临床总有效率、妊娠率以及治疗前后子宫内膜厚度的变化。结果治疗后观察组的总有效率为82.35%,妊娠率为32.35%,治疗组的总有效率为94.12%,妊娠率为61.76%,治疗组均高于对照组(P<0.05);治疗6个月后2对照组子宫内膜厚度都较前增加(P<0.05),且治疗组增加幅度显著优于对照组(P<0.05)。结论麒麟丸联合克罗米芬治疗肾虚型排卵障碍性不孕,疗效确切,临床妊娠率高,并且可明显改善患者子宫内膜的厚度,值得临床推广应用。

Objective:To analyze the clinical effect of Qilin Pills combined with clomiphene in the treatment of infertility patients with kidney deficiency due to ovulation dysfunction.Methods:68 patients were selected according to TCM differentiation and were divided into an observation group and a control group according to the random data table,34 cases per group.The control group was treated with clomiphene and the treatment group was added Qilin Pills on the base of clomiphene treatment.The clinical total effective rate,pregnancy rate and the change of endometrial thickness before and after treatment of the two groups were observed.Results:After treatment,the total effective rate of the observation group was 82.35%,the pregnancy rate was 32.35%,and the total effective rate of the treatment group was 94.12%,and the pregnancy rate was 61.76%.The treatment group was better than the control group(P<0.05).After 6-month treatment,the endometrial thickness of the two groups increased(P<0.05),and the increase in the treatment group was significantly better than that of the control group(P<0.05).Conclusion:Qilin Pills combined with clomiphene has a definite curative effect in the treatment of infertility patients with kidney deficiency due to ovulation dysfunction,with a high clinical pregnancy rate,and can significantly improve the endometrial thickness of the patients,and is worthy of clinical application.