高危良性前列腺增生患者前列腺介入栓塞治疗疗效观察

Prostatic artery embolization for high-risk patients with benign prostatic hyperplasia:A clinical effect observation

目的:探讨前列腺动脉介入栓塞术(PAE)在高危良性前列腺增生(BPH)患者中的临床应用效果。方法:选取2016年1月至2018年6月9例高危BPH患者进行PAE治疗,对其随访半年以上,对患者术前、术后6个月、术后12个月、术后2年或以上的IPSS、生活质量指数(QOL)、残余尿(PVR)、最大尿流率(Qmax)、前列腺体积(PV)、无干扰睡眠时间(HUS)、焦虑自评量表(SAS)和术后并发症发生情况进行对比分析。结果:经PAE手术治疗,随访患者术后6个月、12个月、≥24个月的IPSS、QOL、PVR、Qmax、PV、HUS、SAS等参数均得到显著改善(P<0.05),仅1例出现臀部轻度麻木,经针灸后逐渐好转。结论:PAE对膀胱容量≥200 ml高危BPH患者疗效确切,并发症少,是高危BPH患者改善排尿症状的有效补充治疗途径。

Objective:To observe the clinical effect of prostatic artery embolization(PAE)in the treatment of high-risk patients with BPH.Methods:Nine high-risk patients with BPH underwent PAE in the Third Affiliated Hospital of Anhui Medical University from January 2016 to June 2018.We followed up the patients and obtained their IPSS,quality of life score(QOL),postvoid residual urine volume(PVR),maximum urinary flow rate(Qmax),prostate volume(PV),hours of undisturbed sleep(HUS),Self-Rating Anxiety Scale score(SAS)and incidence of postoperative complications before and at 6,12 and 24 months or longer after surgery,followed by comparative analysis of the parameters.Results:Compared with baseline,IPSS,QOL,PVR,Qmax,PV,HUS and SAS were all significantly improved in the patients at 6,12 and≥24 months after PAE(P<0.05).Only 1 case complained of mild numbness in the buttocks,which was gradually relieved after acupuncture therapy.Conclusion:Prostatic artery embolization is definitely effective for the treatment of high-risk patients with BPH with the bladder volume≥200 ml,with few postoperative complications,and can be used as an effective therapeutic supplementary for improving the urination symptoms of the patients.