脑出血血肿扩大的研究进展

Progress in hematoma expansion in patients with intracerebral hemorrhage

脑出血具有高发病率、高病死率及高致残率等特点,且目前缺乏有效的治疗手段。早期血肿扩大的发生与脑出血患者预后不良风险增加高度相关,而且该过程被认为是可以干预的重要治疗靶点,因此,早期识别血肿扩大发生风险较高的患者并给予积极治疗对改善脑出血预后至关重要。本文现对脑出血血肿扩大的定义、发生机制、预测指标及治疗等方面的研究进展作一综述。

Intracerebral hemorrhage is characterized by high prevalence,mortality and disability rate,and unfortunately few proven treatments are available at present.Early hematoma expansion is significantly associated with worse outcome in patients with intracerebral hemorrhage.Therefore,it is of great importance to early identify the patients with high risk of hematoma expansion,and to provide them with active interventions to improve the prognosis.In the current study,we have reviewed the progress in definition,mechanism,predictive factors and treatments of hematoma expansion in patients with intracerebral hemorrhage.