陈渭良伤科油联合伤科黄水治疗创伤性创面的临床疗效观察

Clinical Observation of CHEN Wei-Liang’s Traumatology Oil Combined with Shangke Huangshui Medicated Gauze in the Treatment of Traumatic Wound

【目的】探究陈渭良伤科油(简称伤科油)联合伤科黄水在治疗创伤性创面中的临床疗效。【方法】将98例由各类外伤导致的创伤性创面患者随机分为观察组52例和对照组46例。2组患者均给予手术室麻醉下创口彻底清创处理,在此基础上,观察组患者给予伤科油联合伤科黄水换药治疗,对照组患者给予常规换药治疗,疗程为14 d并随访3~6个月。观察2组患者治疗前后创面面积和创面肉芽组织覆盖率的变化情况,比较2组患者的创面愈合时间及创面愈合情况。【结果】(1)治疗7 d和治疗14 d后,2组患者的创面面积均较治疗前明显缩小,创面肉芽组织覆盖率均较治疗前明显提高,差异均有统计学意义(P<0.05或P<0.01);组间比较,观察组治疗7 d和治疗14 d后的创面面积均小于对照组,创面肉芽组织覆盖率均高于对照组,差异均有统计学意义(P<0.05或P<0.01)。(2)相对于对照组,观察组患者的创面愈合时间明显缩短,差异有统计学意义(P<0.01)。(3)观察组患者创面的Ⅰ期、Ⅱ期和Ⅲ期愈合率分别为19.23%(10/52)、71.15%(37/52)、9.62%(5/52),对照组分别为8.70%(4/46)、52.17%(24/46)、39.13%(18/46);组间比较,观察组患者创面的Ⅰ期、Ⅱ期愈合率明显高于对照组,Ⅲ期愈合率明显低于对照组,差异有统计学意义(P<0.01)。【结论】采用伤科油联合伤科黄水治疗创伤性创面的疗效明显优于常规治疗,患者的创面愈合时间明显缩短,创面愈合效果明显提高。

Objective To investigate the efficacy of CHEN Wei-Liang’s Traumatology Oil combined with Shangke Huangshui Medicated Gauze for the treatment of traumatic wound. Methods Ninety-eight patients with traumatic wound induced by various traumatic injuries were randomly divided into observation group(52 cases)and control group(46 cases). The two groups were given thorough debridement under the anesthesia in the operative room. And then the observation group was given external application of CHEN Wei-Liang’s Traumatology Oil combined with Shangke Huangshui Medicated Gauze,and the control group was given conventional dressing change treatment.The treatment for the two groups lasted for 14 days,and the patients in the two groups were followed-up for 3-6 months. Before and after treatment,the wound area and the coverage rate for the wound granulation tissue in the two groups were observed. After treatment,the wound healing time and wound healing rate between the two groups were compared. Results(1)After treatment for 7 and 14 days,the wound area was much reduced and the coverage rate for the wound granulation tissue was much increased in the two groups in comparison with those before treatment,the difference being statistically significant(P<0.05 or P<0.01). The intergroup comparison showed that after treatment for 7 and 14 days,the wound area was less and the coverage rate for the wound granulation tissue was higher in the observation group than those in the control group, the difference being statistically significant(P<0.05 or P<0.01).(2)In comparison with the control group, the wound healing time in the observation group was shorter than that in the control group, the difference being statistically significant(P <0.01).(3)The phase Ⅰ,Ⅱ,Ⅲ wound healing rates in the observation group were 19.23%(10/52),71.15%(37/52), 9.62%(5/52)respectively, and those in the control group were 8.70%(4/46), 52.17%(24/46),39.13%(18/46)respectively. The intergroup comparison showed that the phase Ⅰ,Ⅱ wound healing rates in the observation group were higher and phase Ⅲ wound healing rate was obviously lower than those in the observation group,and the difference was statistically significant(P < 0.01). Conclusion External application of CHEN WeiLiang’s Traumatology Oil combined with Shangke Huangshui Medicated Gauze is more effective for the treatment of traumatic injury than conventional dressing change treatment. The combined therapy is effective on shortening the wound healing time and enhancing the wound healing effect.