2012―2018年重庆市缺血性脑卒中发病死亡趋势

Trend change of ischemic stroke incidence and mortality between 2012 and 2018 in Chongqing

目的了解重庆市缺血性脑卒中发病死亡趋势变化,为开展脑卒中防治提供建议。方法2012―2018年缺血性脑卒中个案资料来源于重庆市心脑血管疾病监测,采用SPSS 25.0软件分析计算发病率、标化发病率、死亡率、标化死亡率、构成比。不同地区、不同性别发病率与死亡率的比较采用χ2检验。率的趋势变化采用年度变化百分比(annual percent change,APC)表示。结果2012年重庆市缺血性脑卒中发病率、标化发病率分别为172.78/10万、140.80/10万,2018年发病率、标化发病率分别为186.63/10万、139.17/10万,APC分别为1.71%、0.80%,变化趋势差异无统计学意义(均有P>0.05)。缺血性脑卒中发病率男性高于女性,城市高于农村(均有P<0.05)。农村地区缺血性脑卒中发病率以年均6.29%的速度上升(t=2.83,P=0.037)。缺血性脑卒中死亡率与标化死亡率分别由2012年17.89/10万、16.11/10万上升至2018年的39.03/10万、26.12/10万,分别以年均15.37%(t=6.68,P=0.001)与7.79%(t=5.43,P<0.001)的速度上升。缺血性脑卒中死亡率男性高于女性(均有P<0.05)。农村地区缺血性脑卒中死亡率与标化死亡率分别以年均14.91%(t=8.72,P<0.001)与12.86%(t=7.63,P=0.001)上升。结论重庆市缺血性脑卒中发病率与死亡率较高,发病率相对稳定,死亡率上升,男性与农村是缺血性脑卒中防治重点。

Objective To understand the trend change of ischemic stroke incidence and mortality between 2012 and 2018 in Chongqing,so as to provide suggestions for ischemic stroke prevention and control.Methods Cases of the ischemic stroke,were collected from the surveillance system of cardiovascular and stroke from 2012 to 2018 in Chongqing.Indicators including incidence,age standardization incidence rate(ASIR),mortality,age standardized mortality rate(ASMR),and proportion of ischemic stroke were analyzed by SPSS 25.0.The differences of the ischemic stroke incidence and mortality were compared by Chi-square test between male and female,urban and rural area.The trend change of the incidence and mortality of ischemic stroke were indicated by annual change percent(APC).Results The incidence and ASIR of ischemic stroke were 172.78/100000 and 140.80/100000 in 2012,Chongqing.The incidence and ASIR of ischemic stroke were 186.63/100000 and 139.17/100000 in 2018,Chongqing.APC of incidence and ASIR were 1.71%and 0.80%.And the trend changes of the incidence and ASIR had no significance(all P>0.05).The incidence of ischemic stroke in male was higher than that in female(all P<0.05).The incidence of ischemic stroke in urban area was higher than that in rural area(all P<0.05).The incidence of ischemic stroke increased by 6.29%annually in rural area(t=2.83,P=0.037).The mortality and ASMR of ischemic stroke increased from 17.89/100000,16.11/100000 in 2012 to 39.03/100000,26.12/100000 in 2018 significantly.And its APC were 15.37%(t=6.68,P=0.001)and 7.79%(t=5.43,P<0.001).The mortality of ischemic stroke in male were higher than that in female(all P<0.05).The mortality and ASMR of ischemic stroke increased by 14.91%(t=8.72,P<0.001)and 12.86%(t=7.63,P=0.001)in rural area significantly.Conclusion The incidence and mortality of ischemic stroke in Chongqing were high.The incidence of ischemic stroke was stable in Chongqing.However,the mortality of ischemic stroke increased rapidly in Chongqing.The male and rural area were crucial for ischemic stroke prevention and control.