摘要
黄芩苷(baicalin)是一种具有生物活性的黄酮类化合物,其为多年生草本植物黄芩的主要有效成分。目前相关细胞实验与动物实验均表明,黄芩苷具有多种生物学功能,该文通过查阅近年来国内外的最新相关文献,着重从黄芩苷保肝、护脑、抗氧化、抗糖尿病、抗肿瘤以及与microRNA的作用等方面的功能及其作用机理进行综述,旨在为黄芩苷的进一步开发及临床应用提供新的参考依据。
Baicalin is a biologically active flavonoid compound,which is the main active ingredient of the perennial herb Scutellaria baicalensis.At present,relevant cell experiments and animal experiments have shown that baicalin has a variety of biological functions.This paper reviews the latest literatures at home and abroad in recent years.The functional studies and mechanism of baicalin on liver protection,brain protection,antioxidant,anti-diabetes,anti-tumor,as well as its effect on microRNA are reviewed.This study provides a new reference for the further development and clinical application of baicalin.
作者
杨献光
孙阁阁
丁翠红
文萍萍
YANG Xianguang;SUN Gege;DING Cuihong;WEN Pingping(College of Life Science,Henan Normal University,Xinxiang 453007,China;State Key Laboratory Cultivation Base for Cell Differentiation Regulation,Henan Normal University,Xinxiang 453007,China)
出处
《中国细胞生物学学报》
CAS
CSCD
2021年第4期850-855,共6页
Chinese Journal of Cell Biology
基金
国家自然科学基金(批准号:U1704182)
河南省青年骨干教师项目(批准号:2017GGJS045)资助的课题。
关键词
黄芩苷
黄芩
功能机理
研究概况
baicalin
Scutellaria baicalensis
functional mechanism
review