乳腺癌超声检查参数与病理及转移的相关性分析

Correlation Analysis of Ultrasound Parameters with Pathology and Metastasis of Breast Cancer

目的探讨乳腺癌超声检查参数与病理及转移相关性。方法选取63例乳腺癌患者作为研究对象,将其作为研究组,所有患者均行手术或空心针穿刺病理证实为乳腺癌,另取同期60例良性乳腺肿瘤患者作为对照组。两组患者均行超声检查,对比不同组患者的超声检查结果,并分析超声检查参数与病理确诊为乳腺癌患者的相关性。63例乳腺癌患者经检查确认,出现淋巴结转移的患者32例,分为转移组,未出现淋巴结转移的患者31例,分为未转移组,对比两组乳腺癌患者的超声检查参数,并分析超声检查参数与乳腺癌转移的相关性。结果观察组与对照组患者病灶形态、边界、纵横比、后方回声、血流分级、微钙化超声的图像特征上对比差异显著(P<0.05);观察组与对照组患者的上升支斜率、峰值强度、达峰时间对比差异显著(P<0.05);Spearman相关分析结果显示:病灶形态、边界、纵横比、血流分级、微钙化、上升支斜率、峰值强度、后方回声、达峰时间、始增时间与乳腺癌病理相关(P<0.05);肿块直接大小、微小钙化、血流信号、边界、高回声晕对比差异显著(P<0.05);转移组与非转移组患者阻力指数与肿块最大直径对比差异显著(P<0.05);Spearman相关分析结果显示:肿块直径大小、微小钙化、血流信号、高回声晕、肿块最大直径、边界、阻力指数与淋巴结转移呈负相关(P<0.05)。结论应用乳腺超声检查参数可以判断乳腺癌患者的病理情况与转移情况。

Objective To investigate the correlation between ultrasound parameters and pathology and metastasis of breast cancer.Methods 63 breast cancer patients were selected as the research object and used as the research group.All patients underwent surgery or hollow needle puncture and pathologically confirmed breast cancer,and 60 cases of benign breast cancer patients in the same period were selected as the control group.Ultrasound examination was performed in both groups.The ultrasound results of different groups were compared,and the correlation between ultrasound parameters and pathological diagnosis of breast cancer patients was analyzed.63 cases of breast cancer patients confirmed by examination,32 cases of patients with lymph node metastasis were divided into metastasis group,31 cases of patients without lymph node metastasis were divided into non metastasis group,the ultrasonic parameters of the 2 groups of breast cancer patients were compared,and the correlation between ultrasound parameters and breast cancer metastasis was analyzed.Results There were significant differences between the observation group and the control group in the shape,boundary,aspect ratio,posterior echo,blood flow classification and microcalcification ultrasound image characteristics(P<0.05);the ascending branch slope,peak intensity,peak time of the observation group and the control group were significantly different(P<0.05);Spearman correlation analysis results showed that:lesion morphology There were significant differences in the direct size,microcalcification,blood flow signal,boundary and hyperechoic halo(P<0.05);there were significant differences in the resistance index and the maximum diameter between the metastatic group and the non metastatic group.Spearman correlation analysis showed that tumor diameter,microcalcification,blood flow signal,hyperechoic halo,maximum tumor diameter,boundary,resistance index were negatively correlated with lymph node metastasis(P<0.05).Conclusion Breast ultrasound parameters can be used to determine the case and metastasis of breast cancer patients.