接骨续筋膏外敷结合小夹板固定治疗伸直型桡骨远端骨折患者79例

79 Cases Clinical Study of External Application of Jiegu Xujin Ointment Combined with Small Splint Fixation for Patients with Extension Type of Distal Radius Fracture

目的:观察接骨续筋膏外敷结合小夹板固定治疗对伸直型桡骨远端骨折患者的有效性和安全性。方法:选择2018年1月至2020年1月本院就诊的79例伸直型桡骨远端骨折患者进行前瞻性研究,患者入院后均行基础对症治疗,有移位者先行手法复位,复位完毕后行小夹板固定治疗联合接骨续筋膏外敷治疗。夹板固定治疗和接骨续筋膏外敷治疗均持续6周,6周后拆除夹板并统计疗效。对比患者治疗前后中医证候积分变化情况以及血清BMP-2、IGF-1、IGF-2、VEGF含量变化情况。结果:患者治愈72例,好转7例。治疗后患者各项中医证候积分及总分均低于治疗前,差异有统计学意义(P<0.05);治疗后患者血清BMP-2、IGF-1、IGF-2、VEGF含量明显高于治疗前,差异有统计学意义(P<0.05)。结论:接骨续筋膏外敷结合小夹板固定对伸直型桡骨远端骨折患者疗效较好,可有效改善患者临床症状并促进骨折愈合。

Objective:To observe the efficacy and safety of external application of Jiegu Xujin ointment combined with small splint fixation for patients with extension type distal radius fractures.Methods:A prospective study was conducted on 79 patients with distal radius fracture extension type who were admitted to the author’s hospital from January 2018 to January 2020.All patients received basic symptomatic treatment after admission.Those with displacement received manual reduction first, and small splint fixation combined with external application of Jiegu Xujin ointment was performed after the reduction was completed.Both splint fixation treatment and external application of Jiegu Xujiin ointment lasted for 6 weeks.After 6 weeks, the splint was removed and the curative efficacy was calculated.The changes of TCM syndrome scores and serum BMP-2,IGF-1,IGF-2,and VEGF levels were compared before and after treatment.Results:72 cases were cured.7 cases were improved.After treatment, the scores and total scores of all TCM syndromes were lower than before treatment(P<0.05);after treatment, the gray value of callus was significantly higher than before treatment(P<0.05);after treatment, serum BMP-2,the levels of IGF-1,IGF-2 and VEGF were significantly higher than before treatment(P<0.05).Conclusion:Jiegu Xujin ointment combined with small splint fixation has a satisfied efficacy on patients with extension type of distal radius fracture, which can effectively improve the clinical symptoms of patients and promote fracture healing.