出生时脏腑积分模型与原发性高血压病的关联性分析

A correlation analysis between visceral integral model at birth and essential hypertension

目的:以出生时五运六气为基础建立脏腑积分模型并探讨其与原发性高血压病罹患性及严重程度的相关性。方法:以2016年9月-2018年12月在福建医大附属协和医院中医科及福建中医药大学附属人民医院心内科门诊及住院的已确诊原发性高血压病的病例共3 784例作为研究对象,以同期非高血压病患者1 259例为对照,将患者出生日期分别进行干支转化,根据运气交司表确定患者出生日期所对应的运气时段,建立脏腑积分模型,用独立T检验分析评估可疑的影响因素,并采用有序二分类Logistic回归,评估脏腑积分与罹患原发性高血压病的关系。采用秩和检验比较不同高血压病严重程度分组及对照组之间各脏腑积分的差异,采用多元Logistic回归,评估脏腑积分与高血压病严重程度之间的相关性。结果:出生时脏腑运气积分中,脾、肾积分是原发性高血压病的罹患性和高血压病2级、3级的危险因素,心、肝、肺积分是保护性因素。肝积分是高血压病1级的危险因素,肺、肾、心、脾积分是保护性因素。结论:先天脏腑积分与原发性高血压病的罹患及严重程度存在相关性。

Objective: To correlation analysis between visceral integral model based on the Wuyun Liuqi(五运六气) at birth and essential hypertension. Methods: From September 2016 to December 2018, 3 784 patients with hypertension who had been diagnosed were selected as the research objects, and 1 259 non-hypertensive patients in the same period were taken as the contrast. According to the birth date, the viscera integral model was established. The relationship between visceral integral and essential hypertension was evaluated by independent t-test and ordinal binary logistic regression. Kruskal-Wallis test was used to compare the difference of visceral scores between different hypertension severity groups and the contrast group. Multiple logistic regression was used to evaluate the correlation between visceral scores and the severity of hypertension. Results: Spleen score and kidney score were risk factors of predisposition of hypertension and grade 2 and 3 of hypertension, while heart score, liver score and lung score were protective factors. Liver score is the risk factor of grade 1 hypertension, while lung score, kidney score, heart score and spleen score are protective factors. Conclusion: There is correlation between congenital viscera integral and the incidence and severity of essential hypertension.