从“瘀、毒”病机学说论治溃疡性结肠炎

Treating ulcerative colitis based on stagnation and toxin pathogenesis

溃疡性结肠炎是一种原因尚不十分清楚的直肠与结肠慢性非特异性炎症性疾病,属难治性疾病。笔者基于中医理论,通过长期的临床实践,在深入剖析溃结病因、病机的基础上,结合患者的临床症状,首次提出本病具有"瘀毒"的致病病机特点,"瘀、毒"病机要素贯穿于溃结的整个发展过程,与溃疡性结肠炎的发病密切相关。化瘀解毒之法贯穿于病程之始终,三黄七黛散有活血化瘀,祛腐生新,清热解毒,清化湿热之功,治疗溃疡性结肠炎临床疗效显著,为本病的治疗探索出一条行之有效的新途径。

Ulcerative colitis is a chronic non-specific inflammatory disease of the rectum and colon for which the cause is not yet fully understood. It is a refractory disease. Based on TCM theories, through long-term clinical practice, on the basis of in-depth analysis of its etiology and pathogenesis, combined with the clinical symptoms of patients, the author first proposed that this disease has the pathogenesis characteristics of stagnation and toxin. The method of removing blood stasis and detoxification runs through the course of the disease. Sanhuang Qidai San(三黄七黛散) has the functions of activating blood and removing stasis, dispelling decay and promoting muscle growth, and detoxification, shows a significant clinical effect on ulcerative colitis, and explores an effective new way for the treatment of the disease.