深化对烧伤脓毒症诊断体系与治疗策略的认识

Deepening the understanding of the diagnostic system and therapeutic strategy for burn sepsis

烧伤患者由于大面积皮肤缺损引起创面感染、大量体液流失、高代谢状态等,导致序贯性多系统功能紊乱,极易诱发全身性感染甚至脓毒症。目前,脓毒症已成为严重烧伤患者死亡的首要原因,早期诊断和及时治疗是患者救治成功的关键。烧伤脓毒症具有独特的病理生理特点,一般脓毒症诊断标准对其缺乏特异性。因此,理解烧伤脓毒症的发病机制,有助于深化对烧伤脓毒症诊断体系和干预途径的认识,制订更加精准化、智能化的治疗策略。

Burn patients with large area of skin defect are prone to cause wound infection,severe fluid loss,and hypermetabolism,etc,which lead to sequential dysfunction of multiple systems and easily induce severe systemic infections and sepsis.At present,sepsis has been the leading causes of death in severe burn patients,and its early diagnosis and timely treatment are critical for successful treatment of patients.As burn sepsis has unique pathophysiological characteristics,the diagnostic criteria for general sepsis lack specificity for burn sepsis.Therefore,to understand the pathogenesis of burn will help deepen the understanding of the diagnostic system and interventional way of burn sepsis,thus developing more precise and intelligent therapeutic strategy.