喉鳞状细胞癌的治疗进展

Progress in Treatment of Laryngeal Squamous Cell Carcinoma

喉鳞状细胞癌(LSCC)是一种常见的恶性程度较高的肿瘤,复发率和转移率较高。LSCC的治疗效果主要取决于患者因素和疾病因素,而其治疗方案的选择取决于肿瘤大小、是否转移、患者健康状况、年龄以及经济因素等。LSCC的治疗目的是消灭肿瘤,并保存喉器官及其功能。其治疗方法包括手术切除(经口机器人手术、经口激光显微切除术、全喉切除术)和非手术治疗(同步放化疗、交替放化疗等)。近年来由于患者对治疗后生活质量要求较高,非手术治疗方法在LSCC的治疗中占据越来越重要的地位。因此,未来应深入了解LSCC的生物学特性,掌握LSCC保喉治疗和个体化治疗方法,以为患者提供最佳的治疗方式。

Absract: Laryngeal squamous cell carcinoma( LSCC) is a common malignant tumor with high recurrence and metastasis rate. Its therapeutic effect depends on patient factors and disease factors. The choice of treatment options depends on tumor size,metastasis,patient’s health status,age and economic factors. The purpose of LSCC treatment is to exterminate the tumor and preserve the laryngeal organ and its function. The treatment of LSCC includes surgical resection( peroral robotic surgery,peroral laser microsurgery,total laryngectomy) and non-surgical conservative treatment( concurrent chemoradiation,alternating chemoradiotherapy etc.). In recent years,as the patients have higher requirements for the quality of life after treatment,nonsurgical treatment methods have become more and more important in the treatment of LSCC. Therefore,We should further understanding the biological characteristics of LSCC in the future,mastering the laryngeal protection treatments and individualized treatment methods,can provide the optimal treatment for the patients.