维生素A与新生儿呼吸系统疾病关系的研究进展

Research progress on the association between vitamin A and neonatal respiratory diseases

维生素A是一种脂溶性维生素,它参与广泛的生理过程,如胚胎发育,视觉发育以及细胞分化和增殖。视黄酸(RA)是维生素A主要的活性形式,它调节着多个器官的发育过程。在早期肺发育形成过程中需要足够的维生素A。慢性维生素A缺乏与肺的组织病理学变化有关,这种变化会破坏正常的肺生理,从而导致严重呼吸系统疾病。本文主要对维生素A与新生儿呼吸系统疾病关系做一总结,为临床治疗提供一定的指导。

Vitamin A is a fat-soluble vitamin that participates in a wide range of physiological processes,such as embryonic development,visual development,cell differentiation and proliferation.Retinoic acid(RA)is the main active form of vitamin A,which regulates the development of multiple organs.Sufficient vitamin A is needed during early lung development.Chronic vitamin A deficiency is related to the histopathological changes of the lungs,which can disrupt normal lung physiology,leading to severe respiratory diseases.This review mainly summarizes the relationship between vitamin A and neonatal respiratory diseases,thus to provide guidance for clinical treatment.