多金属氧酸盐抗病毒研究进展

Research Progress of Polyoxometalates Antiviral

多金属氧酸盐是由杂原子(如P、Si等)和过渡金属原子(如W、V等)按一定的结构通过氧原子配位桥联组成的一类含氧化合物。本文主要综述了其在抗艾滋病毒、抗流感病毒、抗肝炎病毒的体内外研究进展,并总结了其抗病毒机制,最后分析了其抗新冠病毒的可行性。

Polyoxometalate is a kind of oxygen-containing compound composed of heteroatoms(such as P,Si etc.)and transition metal atoms(such as W,V etc.)in a certain structure via coordination bridge of oxygen atoms.In this review,we discussed the development progress of its anti-HIV,anti-influenza and anti-hepatitis virus effect,both in vivo and in vitro,highlighting the mechanism of its anti-virus effect,as well as the possibility for anti-COVID-19 treatment.