尖吻蝮蛇血凝酶联合酚妥拉明或垂体后叶素治疗支气管扩张伴咯血的疗效对比

Comparison on Efficacy of Deinagkistrodon Acutus Hemocoagulase Combined with Phentolamine or Pituitrin in the Treatment of Bronchiectasis Complicated with Hemoptysis

目的比较尖吻蝮蛇血凝酶联合酚妥拉明或垂体后叶素治疗支气管扩张伴咯血的疗效。方法选取我院2018年1月至2020年1月收治的60例支气管扩张伴咯血患者,随机将其分为对照组和观察组各30例。两组均给予镇咳、抗感染、体位引流等常规治疗。对照组采用尖吻蝮蛇血凝酶联合酚妥拉明治疗,观察组采用尖吻蝮蛇血凝酶联合垂体后叶素治疗。比较两组的临床疗效、咯血血止时间、住院时间。结果观察组的总有效率高于对照组,咯血血止时间、住院时间均短于对照组(P<0.05)。结论尖吻蝮蛇血凝酶联合垂体后叶素治疗支气管扩张伴咯血疗效更佳,可有效缩短咯血血止时间及住院时间,促进患者康复。

Objective To compare the efficacy of Deinagkistrodon acutus hemocoagulase combined with phentolamine or pituitrin in the treatment of bronchiectasis complicated with hemoptysis.Methods 60 cases of patients with bronchiectasis complicated with hemoptysis admitted to our hospital from January 2018 to January 2020 were selected and randomly divided into control group and observation group,with 30 cases in each group.Both groups were given routine treatment of antitussive,anti-infection and postural drainage.The control group was treated with Deinagkistrodon acutus hemocoagulase combined with phentolamine,and the observation group was treated with Deinagkistrodon acutus hemocoagulase combined with pituitrin.The clinical efficacy,hemoptysis time and hospitalization time were compared between the two groups.Results The total effective rate of the observation group was higher than that of the control group,and the hemoptysis time and hospitalization time were shorter than those of the control group(P<0.05).Conclusions Deinagkistrodon acutus hemocoagulase combined with pituitrin has better efficacy in the treatment of bronchiectasis complicated with hemoptysis,which can effectively shorten the hemoptysis time and hospitalization time,and promote the recovery of patients.