术中快速冰冻切片在甲状腺乳头状癌诊断中的应用分析

Analysis on Application of Intraoperative Rapid Frozen Section in the Diagnosis of Papillary Thyroid Carcinoma

目的探讨术中快速冰冻切片在甲状腺乳头状癌诊断中的应用效果。方法选取2016年4月至2020年7月我院收治的56例甲状腺乳头状癌患者,入选患者门诊检查疑为甲状腺癌,入院1周内行甲状腺切除术,术中均行冰冻切片病理检查及石蜡包埋切片检查,记录冰冻切片检查的准确率及术后并发症情况。结果术中快速冰冻切片共检出甲状腺乳头状癌48例,延期诊断2例,误诊6例,诊断准确率为85.7%。不同年龄段患者术中快速冰冻切片诊断结果比较差异无统计学意义(P>0.05)。56例患者中有6例出现术后并发症,其中2例术后出血,经止血处理后止血;3例声音嘶哑,疑为喉返神经损伤,出院前基本恢复;1例出现术后低钙血症。结论术中快速冰冻切片在甲状腺乳头状癌中具有较好的诊断价值,值得推广。

Objective To explore the application effect of intraoperative rapid frozen section in the diagnosis of papillary thyroid carcinoma.Methods 56 patients with papillary thyroid carcinoma admitted to our hospital from April 2016 to July 2020 were selected.The selected patients were suspected of thyroid cancer after outpatient examination,and thyroidectomy was performed within 1 week after admission.Pathological examination of frozen section and paraffin embedded section were performed during operation.The accuracy of frozen section examination and postoperative complications were recorded.Results Intraoperative rapid frozen section showed that 48 cases were papillary thyroid carcinoma,2 cases were delayed diagnosis,and 6 cases were misdiagnosed,with the diagnostic accuracy rate of 85.7%.No statistical difference was found in the diagnostic results of intraoperative rapid frozen section among patients with different ages(P>0.05).Among 56 cases of patients,6 cases had postoperative complications.2 cases had postoperative bleeding,which was stopped after hemostasis;3 cases had hoarseness,who were suspected of recurrent laryngeal nerve injury,and recovered before discharge.1 case had postoperative hypocalcemia.Conclusions Intraoperative rapid frozen section has good diagnostic value in papillary thyroid carcinoma,which is worthy of promotion.