低频超声对颈动脉粥样硬化患者颈动脉狭窄程度和血脂指标的影响研究

Effect of Low Frequency Ultrasound on Carotid Artery Stenosis and Blood Lipid Index in Patients with Carotid Atherosclerosis

目的:探讨采用低频超声治疗颈动脉粥样硬化,对患者颈动脉狭窄程度和血脂指标的具体影响。方法:选取笔者所在医院2018年12月-2019年12临床收治的颈动脉粥样硬化患者108例为研究对象,随机将患者分为研究组和对照组,每组54例。研究组给予药物联合低频超声治疗,对照组给予口服药物治疗。对两组治疗不同时点动脉内膜厚度、颈动脉斑块直径、颈动脉斑块积分、血脂指标及治疗后颈动脉中重度狭窄率进行观察和比较。结果:治疗前,两组颈动脉内膜厚度、颈动脉斑块直径和颈动脉斑块积分比较差异无统计学意义(P>0.05);治疗3周时,研究组动脉内膜厚度低于对照组,差异有统计学意义(P<0.05);治疗6周时,研究组动脉内膜厚度、颈动脉斑块直径和颈动脉斑块积分均优于对照组,差异均有统计学意义(P<0.05)。治疗前两组TG、TC、HDL-C和LDL-C比较差异无统计学意义(P>0.05);治疗3、6周时,研究组TC和LDL-C均低于对照组,差异均有统计学意义(P<0.05)。治疗后,研究组颈动脉中重度狭窄率为14.81%,低于对照组的31.48%,差异有统计学意义(P<0.05)。结论:采用低频超声治疗颈动脉粥样硬化,能够降低患者动脉内膜厚度,改善患者颈动脉狭窄程度和血脂指标,具有较好的临床应用价值。

Objective:To investigate the effect of low frequency ultrasound on carotid artery stenosis and blood lipid index in patients with carotid atherosclerosis.Method:From December 2018 to December 2019,108 patients with carotid atherosclerosis in our hospital were selected and randomly divided into the study group and the control group,with 54 cases in each group.Patients in the study group were given drugs combined with low frequency ultrasound treatment,and the control group were given oral drug treatment.The intimal thickness,carotid plaque diameter,carotid plaque score,blood lipid index and carotid artery stenosis rate were observed and compared between the two groups at different time points.Result:Before treatment,there were no significant differences in carotid intima thickness,carotid plaque diameter and carotid plaque score between the two groups(P>0.05),after 3 weeks of treatment,the intima thickness in the study group was lower than that in the control group,the difference was statistically significant(P<0.05),after 6 weeks of treatment,the intima thickness,carotid plaque diameter and carotid plaque score in the study group were better than those in the control group,the differences were statistically significant(P<0.05).Before treatment,there were no significant differences in TG,TC,HDL-C and LDL-C between the two groups(P>0.05),after 3 and 6 weeks of treatment,TC and LDL-C in the study group were lower than those in the control group,the differences were statistically significant(P<0.05).After treatment,the moderate and severe carotid stenosis rate in the study group was 14.81%,which was lower than 31.48%in the control group,the difference was statistically significant(P<0.05).Conclusion:Low frequency ultrasound in treatment of carotid atherosclerosis can reduce the intimal thickness of patients,improve the degree of carotid stenosis and blood lipid indicators,and has good clinical application value.