雾化吸入特布他林对MP患儿的疗效及Th17、Treg细胞水平的影响

The Curative Effect of Nebulized Terbutaline on Children with MP and the Effect on Th17 and Treg Cell Levels

目的:探讨雾化吸入特布他林对支原体肺炎(MP)患儿的疗效及Th17、Treg细胞水平的影响。方法:选取本科收治的2018年1月-2020年6月的60例MP患儿作为研究对象,随机分为对照组(阿奇霉素,n=30)、研究组(雾化特布他林联合阿奇霉素,n=30)。比较治疗有效率、炎性反应、Th17、Treg细胞水平。结果:研究组治疗总有效率高于对照组(P<0.05);研究组患儿IFN-γ、IL-2、IL-4水平低于对照组(P<0.06);研究组患儿Th17、Treg细胞含量优于对照组(P<0.05)。结论:对于MP患儿,辅以雾化特布他林可降低机体炎性反应,提高机体免疫功能,从而提高疗效。

Objective:To investigate the effect of nebulized Terbutaline on children with mycoplasma pneumonia(MP)and the effect of Th17 and Treg cell levels.Method:A total of 60 children with MP who were admitted to our department from January 2018 to June 2020 were selected as the study objects,and they were randomly divided into the control group(Azithromycin,n=30)and the study group(nebulized Terbutaline combined Azithromycin,n=30).Treatment efficiency,inflammatory response,Th17 and Treg cell levels were compared.Result:The total effective rate of treatment in the study group was higher than that in the control group(P<0.05);the levels of IFN-γ,IL-2,and IL-4 in the study group were lower than those in the control group(P<0.06);Th17,Treg in the study group were better than the control group(P<0.05).Conclusion:For children with MP,supplemented with nebulized Terbutaline can reduce the body’s inflammatory response and improve the body’s immune function,thereby improving the efficacy.