全膀胱切除术后原位回盲肠新膀胱重建术联合中医埋针、穴位贴敷治疗膀胱癌的临床效果

Clinical effect of reconstruction of ileocecal neobladder in situ after total cystectomy combined with TCM imbedding needle and acupoint application in the treatment of bladder cancer

目的探究全膀胱切除术后原位回盲肠新膀胱重建术联合中医埋针、穴位贴敷治疗膀胱癌的临床效果。方法将2018年1月至2020年1月我院收治的80例膀胱癌患者根据随机数字表法分为对照组和观察组,各40例。对照组采用全膀胱切除术后原位回盲肠新膀胱重建术治疗,观察组在对照组基础上联合中医治疗理念,采用中医埋针和穴位贴敷治疗。比较两组的手术相关指标、并发症发生情况、生活质量及炎症因子水平。结果两组的手术时间、术中出血量、尿管拔除时间和住院时间比较,差异无统计学意义(P>0.05)。观察组术后并发症总发生率显著低于对照组,差异具有统计学意义(P<0.05)。治疗后,观察组生理机能、生理职能、躯体疼痛、一般健康状况、精力、社会功能、情感职能、精神健康评分均高于治疗前和对照组,差异具有统计学意义(P<0.05)。治疗后,观察组CRP、IL-6和TNF-α水平均低于治疗前及对照组,差异具有统计学意义(P<0.05)。结论全膀胱切除术后原位回盲肠新膀胱重建术联合中医埋针、穴位贴敷治疗膀胱癌的效果明显,可减少术后并发症的发生,提高生活质量,降低炎性因子水平,且创伤小、术后恢复快,值得推广。

Objective To explore the clinical effect of reconstruction of ileocecal neobladder in situ after total cystectomy combined with TCM imbedding needle and acupoint application in the treatment of bladder cancer.Methods A total of 80 patients with bladder cancer admitted in our hospital from January 2018 to January 2020 were divided into control group and observation group by random number table methed,with 40 cases in each group.The control group was treated with reconstruction of ileocecal neobladder in situ after total cystectomy,and the observation group combined with the treatment concept of traditional Chinese medicine on the basis of the control group,and treated with TCM imbedding needle and acupoint application.The operation related indexes,complications,quality of life and inflammatory factors of the two groups were compared.Results There were no significant differences in operation time,intraoperative blood loss,catheter removal time and hospital stay between the two groups(P>0.05).The total incidence of postoperative complications in the observation group was significantly lower than that in the control group,and the difference was statistically significant(P<0.05).After treatment,the scores of physical function,physiological function,physical pain,general health status,energy,social function,emotional function and mental health in the observation group were higher than those before treatment and in the control group,and the differences were statistically significant(P<0.05).After treatment,the levels of CRP,IL-6 and TNF-αin the observation group were lower than those before treatment and in the control group,and the differences were statistically significant(P<0.05).Conclusion Reconstruction of ileocecal neobladder in situ after total cystectomy combined with TCM imbedding needle and acupoint application in the treatment of bladder cancer has obvious effect,which can reduce the occurrence of postoperative complications,improve the quality of life,and decrease the levels of inflammatory factors,with less trauma and quick postoperative recovery.It is worthy of promotion.