河南省蔬菜水果双酚S污染的居民膳食暴露风险评估

Dietary exposure risk of bisphenol S in vegetables and fruits in Henan Province

目的分析河南省蔬菜水果双酚S (BPS)污染水平,并评估居民膳食暴露风险,为制订相关的食品安全标准提供依据。方法于2018-2019年采集河南省本地种植、销售的蔬菜水果样品276份,采用同位素稀释-超高效液相色谱-三重四极杆串联质谱法(UPLC-MS/MS)测定BPS;结合当地居民的膳食结构和平均体重计算膳食暴露量,参考类似物双酚A (BPA)的每日耐受摄入量(TDI)计算BPS的风险指数。结果蔬菜和水果中检出BPS含量分别为0.006~12.600μg/kg和0.006~9.380μg/kg,中位数分别为0.053μg/kg和0.023μg/kg,检出率分别为78.43%和62.60%,蔬菜BPS检出率和含量均大于水果(P<0.05)。居民来源于蔬菜水果的BPS最大暴露总量为5.37×10^(-2)μg/(kg体重·d),暴露风险指数为1.07×10^(-3),风险可接受。结论河南省蔬菜和水果中均检出BPS,蔬菜中BPS的检出率和含量均大于水果。居民经蔬菜水果暴露BPS的健康风险较小。

Objective To monitor the content of bisphenol S(BPS) in vegetables and fruits in Henan Province and evaluate the dietary exposure risk of the population,so as to provide the basis for formulating relevant food safety standards.Methods From 2018 to 2019,276 samples of vegetables and fruits produced and sold in Henan Province were collected.BPS was determined by isotope dilution ultra performance liquid chromatography triple quadrupole tandem mass spectrometry(UPLC-MS/MS),and the dietary exposure was calculated according to the dietary structure and average body weight of local residents.The risk index of BPS was calculated according to the daily tolerable intake(TDI) of bisphenol A(BPA).Results The BPS contents in vegetables and fruits were 0.006-12.600 μg/kg and 0.006-9.380 μg/kg,the medians were 0.053 μg/kg and 0.023 μg/kg,the detection rates were 78.43% and 62.60%,respectively.The detection rate and content of BPS in vegetables were higher than those in fruits(P<0.05).The maximum exposure of BPS from vegetables and fruits was 5.37×10^(-2) μg/(kgbw·d),and the exposure risk index was 1.07 × 10^(-3),which was acceptable.Conclusions BPS was detected from vegetables and fruits in Henan Province.The detection rate and content of BPS in vegetables were higher than those in fruits.The health risk of BPS exposed by vegetables and fruits is small.