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紫杉醇治疗妇科肿瘤的疗效观察

Observation on the Therapeutic Effect of Paclitaxel on Gynecological Tumors
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摘要 目的妇科肿瘤患者应用紫杉醇治疗的临床疗效分析。方法随机选取2016年11月—2017年11月收治的80例妇科肿瘤患者,将其按照简单随机化法均分为对照组(40例)和观察组(40例),对照组应用异环磷酰胺,观察组应用紫杉醇,对比两组治疗疗效、生存期及不良反应发生率。结果观察组治疗总有效率(90.00%)高于对照组(72.50%),且观察组生存期优于对照组,观察组不良反应发生率(15.00%)低于对照组(27.50%),差异有统计学意义(P<0.05)。结论对妇科肿瘤患者应用紫杉醇治疗有较好的临床效果,其能有效延长患者的生存期,且不良反应较少。 Objective To analyze the clinical efficacy of paclitaxel in patients with gynecological tumors.Methods Randomly select 80 patients with gynecological tumors admitted from November 2016 to November 2017,and divide them into a control group(40 cases)and an observation group(40 cases)according to a simple randomization method.The control group was treated with ifosfamide,paclitaxel was used in the observation group to compare the therapeutic effect,survival time and incidence of adverse reactions between the two groups.Results The total effective rate of treatment in the observation group(90.00%)was higher than that in the control group(72.50%),and the survival time of the observation group was better than that of the control group.The incidence of adverse reactions(15.00%)in the observation group was lower than that in the control group(27.50%).The difference was statistically significant(P<0.05).Conclusion The use of paclitaxel in patients with gynecological tumors has a good clinical effect.It can effectively prolong the survival time of patients and has fewer adverse reactions.
作者 陈碧琦 何菊芳 CHEN Biqi;HE Jufang(Department of Obstetrics and Gynecology,The Third People's Hospital of Jingzhou,Jingzhou Hubei 434000,China)
出处 《中国继续医学教育》 2021年第16期135-138,共4页 China Continuing Medical Education
关键词 妇科肿瘤 紫杉醇 生存期 不良反应 中性粒细胞 异环磷酰胺 gynecological tumors paclitaxel survival adverse reactions neutrophils ifosfamide
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