妇产科疾病治疗中应用米非司酮的临床观察

Clinical Observation on the Application of Mifepristone in the Treatment of Gynecological and Obstetric Diseases

目的探究米非司酮在妇产科疾病治疗中的应用效果。方法抽取2018年3月—2019年3月在我院接受治疗的妇产科疾病患者78例为研究对象,根据其住院先后顺序从1~78编号,再按等差数列首项为1,公差为2的方式将78例患者平均分为两组,即对照组与试验组,两组患者均为39例。对照组行常规药物治疗,试验组患者予以米非司酮,观察两组患者的治疗效果。结果试验组39例患者中,子宫肌瘤治疗总有效率为100%,终止妊娠治疗总有效率为100%,子宫内膜异位症治疗总有效率为88.89%,紧急避孕治疗总有效率为100%。试验组39例患者中,治愈例数为25例,有效例数为13例,无效例数为1例,治疗总有效率为97.44%,对照组39例患者中,治愈为15例,有效为16例,无效为8例,治疗总有效率为79.49%,χ^(2)=6.154,P<0.05,差异具有统计学意义。结论对妇产科疾病患者予以米非司酮能够进一步提升治疗效果,减少患者的不良反应发生率。

Objective To explore the application effect of mifepristone in the treatment of obstetrics and gynecology diseases.Methods Seventy-eight patients with obstetrics and gynecology who received treatment in our hospital from March 2018 to March 2019 were selected as the research objects.According to their hospitalization sequence,the 78 patients were numbered from 1 to 78,and then divided into two groups according to the way that the first item in the arithmetic sequence was 1 and the tolerance was 2,namely,the control group and the experimental group,with 39 patients in both groups.The control group was treated with conventional drugs,and the experimental group was treated with mifepristone.The therapeutic effect of the two groups was observed.Results In the trial group of 39 patients,the total effective rate of uterine fibroids treatment was 100%,the total effective rate of pregnancy termination treatment was 100%,the total effective rate of endometriosis treatment was 88.89%,and the total effective rate of emergency contraception treatment was 100%.Among the 39 patients in the experimental group,25 cases were cured,13 cases were effective,and 1 case was ineffective,with a total effective rate of 97.44%;among the 39 patients in the control group,15 cases were cured,16 cases were effective,and 8 cases were ineffective,with a total effective rate of 79.49%,χ^(2)=6.154,P<0.05.Conclusion Mifepristone for patients with obstetrics and gynecology diseases can further improve the treatment effect and reduce the incidence of adverse reactions in patients,which deserves widespread clinical application.