抗菌水凝胶在生物医学领域的研究进展

Progress of Antibacterial Hydrogel in Field of Biomedicine

细菌感染是阻碍伤口愈合的重要因素之一,同时也是生物医学领域面临的一个重要问题。目前的抗菌水凝胶有着高抗菌活性、生物相容性以及可注射性等性能,并且其物理化学性质与生物组织相似,使得越来越多新型的抗菌水凝胶材料被用于治疗细菌感染。综述了近几年抗菌水凝胶的研究进展,归纳总结了几种不同类型的抗菌水凝胶的制备方法,抗菌活性和生物相容性等。重点阐述了抗菌水凝胶在伤口敷料、药物负载和传递以及组织工程等生物医学领域中的应用前景。

Bacterial infection is one of the important factors hindering wound healing, and it is also an important problem in biomedical field.The current antibacterial hydrogels have high antibacterial activity, biocompatibility and inject ability, and their physical and chemical properties are similar to those of biological tissues, making more and more new antibacterial hydrogel materials used to treat bacterial infections.The research progress of antibacterial hydrogels in recent years was reviewed, and preparation methods, antibacterial activity and biocompatibility of several kinds of antibacterial hydrogels were summarized.Furthermore, the application prospect of antibacterial hydrogels in wound dressings, drug loading and delivery, tissue engineering and other biomedical fields were emphasized.