维持性血液透析患者蛋白质能量消耗的治疗研究进展

Advances in treatment of protein-energy wasting in maintenance hemodialysis patients

维持性血液透析(maintenance hemodialysis,MHD)患者常出现蛋白质和能量缺乏的营养不良状态,表现为体重减轻、体脂和肌肉量下降、蛋白质分解代谢增加等,国际肾脏营养与代谢协会将这种营养不良状态命名为“蛋白质-能量消耗(protein-energy wasting,PEW)”。PEW与低生活质量、高住院率、高病死率相关,因此,对MHD患者进行营养评估,及早发现并治疗PEW非常重要。文章将对MHD患者PEW治疗领域的研究进展进行综述。

Maintenance hemodialysis(MHD)patients often suffer from protein and energy deficiency,manifested by weight loss,decreased body fat and muscle mass,and increased protein catabolism,etc.International Society of Renal Nutrition and Metabolism(ISRNM)named this malnutrition as"protein-energy wasting(PEW)".PEW is associated with low quality of life,high hospitalization rate and high mortality.Therefore,it is very important to evaluate the nutritional status of MHD patients and detect and treat PEW early.This article will review the research progress of PEW in MHD patients.